Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the procedure of many myeloma. Its synthesis or review is vital for ensuring the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound from the synthesis of imatinib, a drug that targets certain kinds of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is essential for optimizing the generation system and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the synthesis of 2-deoxy-2 adamantane derivatives, that have various programs, which includes antiviral Houses.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-four to manage blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 7-dihydro-4-oxo-1H-pymol[2 2 (SGLT2).